Nicotine is a potent is a nicotinic acetylcholine receptor agonist. It is the main psychoactive in cigarettes. It is often an overlooked stimulant – that’s actually really effective for people with ADHD. It is said that many people probably “self-medicate” with cigarettes, taken alone Nicotine does not seem to have the destructive long term problems of smoking, as most of the risk in smoking is from burning the chemicals. Applied alone in lozenges, gums and patches it seems so far extremely safe, as people have been doing so for many years if not a decade.
To date there is only one research paper linking Nicotine with cancer, and that is to do with gum cells in a Petri dish, there remains no constructive evidence that Nicotine is dangerous on it’s own. Whilst addictive, it does not produce the strong withdrawal effects and synaptic downregulation that Amphetamines, nor does it have the bad comedowns of Ritalin.