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Benzodiazepine

Posted by Joey B. Wong on August 04, 2016  /   Posted in Uncategorized

Benzodiazepines (BZD, BZs), sometimes called “benzos”, are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. The first such drug, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche, which, since 1963, has also marketed the benzodiazepine diazepam (Valium).[1] In 1977 benzodiazepines were globally the most prescribed medications.[2]
Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation.[3] These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures.[4] Benzodiazepines are categorized as either short-, intermediate-, or long-acting. Short- and intermediate-acting benzodiazepines are preferred for the treatment of insomnia; longer-acting benzodiazepines are recommended for the treatment of anxiety.[5]

About Joey B. Wong

Joey Wong, M.A., is a down-to-earth problem solver by nature who is both entrepreneurially-driven and service-minded. Dedicated to creating the most positive change possible, he strives to be on the cutting-edge of technology, so he can help others solve various issues—particularly with their health. As someone who has endured the many hardships of chronic illness, Joey has really made it a point to reach out to those who have been left behind in this world. Currently, Joey runs stardust.bio, which is a hub of valuable information for ardent “information sponges.”If you are interested in his story, check out: https://www.khemcorp.com/the-story-about-the-person-who-runs-khemcorp/

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