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Kratom Potentiation Guide

Posted by Anonymous on October 22, 2015  /   1 comment
kratom potentiation

Thanks to  the guys at  KratomEye for these suggestions for Kratom potentiation. – Black Seed Oil (cumin seed) – Hordenine (very minute amounts, 5 – 20mg, even. MAO-B inhibitor – works great if you don’t use too much) – Tribulus Terrestris (a milder MAO-B inhibitor. This is also great as it boosts testosterone and brings […]

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Memantine Experiences for Drug Tolerance of all Kinds

Posted by Anonymous on September 11, 2015  /   7 comments
memantine opiate potentiation

Memantine the Unknown Drug Tolerance Prevention Chemical Memantine has had been a well kept secret for drug tolerance prevention. Over the years many people have toyed with it hoping to use it to abuse recreational drugs and not develop tolerance, this backfired obviously. Most notably for trying to the higher and higher dosages of Adderall […]

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Where Medical Institutions End and Brain Hacking Begins

Posted by Anonymous on August 26, 2015  /   no comment

Anyone who is not a neurotypical – be it brain damaged from natural cerebral disasters, degenerative diseases or born neuro dysfunctional and different. Knows that medical institutions have a severe limitation when it comes to addressing problems of the mind. Or any problem not deemed worthy of the medical institution to address. In this article […]

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Memantine Reversing Nicotine Tolerance – Research Summary

Posted by Anonymous on August 21, 2015  /   no comment

Article is work in progress. I guess since NMDA receptors have such a role to play in drug tolerance, it isn’t exactly surprising that they seen to attenuate tolerance for alot of other types of drugs as well. Daily treatment for 7 days with nicotine (0.4 mg/kg s.c.) produced tolerance to the CTA and motor […]

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Memantine Research Summary Explained – The Basics

Posted by Anonymous on August 01, 2015  /   no comment
memantine opiate potentiation

Memantine Research Summary Explained – The Basics What is Memantine? Memantine is a novel unique drug that acts on the glutamatergic system by blocking NMDA Receptors, it is mainly prescribed for treating Alzheimer’s disease. Its effects for Alzheimer’s are actually questionable according to some studies, showing that has little use in mild Alzheimer’s, but reasonable […]

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Proglumide Reversing Opiate Tolerance – A Comprehensive Review of Opiate Potentiation

Posted by Anonymous on July 07, 2015  /   no comment
Proglumide Structure

Article is work in progress. Link to the first article here :  Proglumide Summary  A second comprehensive review of patent and medical literature for Opiate Potentiation Why are you revisiting Proglumide? Research is never complete, we have had a lot of people asking us difficult questions with answers we wish we knew. So its important […]

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Memantine Dosage and Titration for Drug Tolerance and ADHD

Posted by Anonymous on November 27, 2014  /   no comment

Short Term Effects on Tolerance Anecdotally, Memantine has possibly immediete effects on opiate and amphetamine tolerance. In these mice, the co-administration of memantine and MRZ 2/579, but not dextromethorphan, resulted in the reversal of morphine tolerance. In experiment 3, memantine and MRZ 2/579 (10 mg/kg) inhibited the acute antinociceptive effect of morphine, but dextromethorphan did […]

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