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Agmatine

Posted by Anonymous on August 04, 2016  /   Posted in

Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is discussed as a putative neurotransmitter. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase. Agmatine binds to α2-adrenergic receptor and imidazoline binding sites, and blocks NMDA receptors and other cation ligand-gated channels. These 3 actions all have effects for reducing the development of drug tolerance.

Agmatine Sulphate is purported and researched to have effects of reducing tolerance to effects of other drugs. Agmatine sulphate is the popular supplement for taking agmatine, it also has uses for sport. It is also incredibly cheap.

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