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Benzo Reversal of Tolerance – Research Summary

Posted by Anonymous on June 07, 2016  /   no comment
benzo reversal

What is Benzodiazepine Tolerance? Benzodiazepine is drug tolerance to benzodiazepine (duh). Examples of benzos are Valium, Xanax, Clonazepam, and Lorazepam. There are many more and they all act strongly on GABA as allosteric modulators – which increases the activity of the protein. Benzo reversal is about reversing the tolerance to benzo type drugs and restoring […]

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Adderall Tolerance – How to Use Memantine to Reduce Tolerance – Research Summary

Posted by Anonymous on February 11, 2016  /   no comment
memantine opiate potentiation

What is Memantine? There is growing interest in Memantine which is a novel unique drug that acts on the glutamatergic system by blocking NMDA Receptors. It is mainly prescribed for treating Attention Deficit Hyperactive Disorder ADHD, narcolepsy, Alzheimer’s disease, autism and some chemical addictive substance abuse. The mechanism of action of this drug is being […]

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Ultra Low Dose Naltrexone – For Lower Opiate Tolerance – Research Summary

Posted by Anonymous on November 04, 2015  /   no comment
Ultra Low Dose Naltrexone Explained

What is Naltrexone? Naltrexone is described as a substituted oxymorphone, it’s active metabolites are antagonists at the u-opioid receptor (MOR), k-opioid receptor (KOR), and the o-opioid receptor (DOR). Naltrexone’s primary use (in normal doses) is in the management of opioid and alcohol dependency. It is also often used to reduce Benzodiazepine withdrawal symptoms as both […]

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Kratom Potentiation Guide

Posted by Anonymous on October 22, 2015  /   no comment
kratom potentiation

Thanks to  the guys at  KratomEye for these suggestions for Kratom potentiation. – Black Seed Oil (cumin seed) – Hordenine (very minute amounts, 5 – 20mg, even. MAO-B inhibitor – works great if you don’t use too much) – Tribulus Terrestris (a milder MAO-B inhibitor. This is also great as it boosts testosterone and brings […]

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Memantine Experiences for Drug Tolerance of all Kinds

Posted by Anonymous on September 11, 2015  /   no comment
memantine opiate potentiation

Memantine the Unknown Drug Tolerance Prevention Chemical Memantine has had been a well kept secret for drug tolerance prevention. Over the years many people have toyed with it hoping to use it to abuse recreational drugs and not develop tolerance, this backfired obviously. Most notably for trying to the higher and higher dosages of Adderall […]

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Opiate Potentiation Guide – The Ultimate List

Posted by Anonymous on September 02, 2015  /   no comment
memantine opiate potentiation

Forewarning About Opiate Potentiators Before we get started, its really important to note that. Opiate potentiation is not the same as tolerance reversal or prevention. The two are often mistaken for each other because they both can increase opiates effects (hence also described as potentiators). However traditional potentiators are different in that they do not […]

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Where Medical Institutions End and Brain Hacking Begins

Posted by Anonymous on August 26, 2015  /   no comment
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Anyone who is not a neurotypical – be it brain damaged from natural cerebral disasters, degenerative diseases or born neuro dysfunctional and different. Knows that medical institutions have a severe limitation when it comes to addressing problems of the mind. Or any problem not deemed worthy of the medical institution to address. In this article […]

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Memantine Reversing Nicotine Tolerance – Research Summary

Posted by Anonymous on August 21, 2015  /   no comment
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Article is work in progress. I guess since NMDA receptors have such a role to play in drug tolerance, it isn’t exactly surprising that they seen to attenuate tolerance for alot of other types of drugs as well. Daily treatment for 7 days with nicotine (0.4 mg/kg s.c.) produced tolerance to the CTA and motor […]

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Memantine Research Summary Explained – The Basics

Posted by Anonymous on August 01, 2015  /   no comment
memantine opiate potentiation

Memantine Research Summary Explained – The Basics What is Memantine? Memantine is a novel unique drug that acts on the glutamatergic system by blocking NMDA Receptors, it is mainly prescribed for treating Alzheimer’s disease. Its effects for Alzheimer’s are actually questionable according to some studies, showing that has little use in mild Alzheimer’s, but reasonable […]

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